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Hoau-Yan Wang Selected Research

S 24795

3/2010S 24795 limits beta-amyloid-alpha7 nicotinic receptor interaction and reduces Alzheimer's disease-like pathologies.
1/2009Dissociating beta-amyloid from alpha 7 nicotinic acetylcholine receptor by a novel therapeutic agent, S 24795, normalizes alpha 7 nicotinic acetylcholine and NMDA receptor function in Alzheimer's disease brain.

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Hoau-Yan Wang Research Topics

Disease

18Alzheimer Disease (Alzheimer's Disease)
01/2022 - 11/2002
4Neuroinflammatory Diseases
01/2022 - 01/2017
4Schizophrenia (Dementia Praecox)
01/2020 - 07/2005
4Cognitive Dysfunction
12/2019 - 04/2012
3Dementia (Dementias)
12/2019 - 02/2014
3Amyloid Plaque
01/2017 - 11/2002
2Carcinogenesis
01/2020 - 01/2019
2Neurodegenerative Diseases (Neurodegenerative Disease)
12/2019 - 01/2017
2Insulin Resistance
02/2014 - 04/2012
1AIDS-Related Complex (ARC)
10/2021
1Inflammation (Inflammations)
01/2021
1Amyloid angiopathy
01/2021
1Body Weight (Weight, Body)
01/2021
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
01/2021
1Brain Infarction
01/2021
1Atherosclerosis
01/2021
1Arteriolosclerosis
01/2021
1Brain Neoplasms (Brain Tumor)
01/2020
1Glioma (Gliomas)
01/2020
1Type 2 Diabetes Mellitus (MODY)
12/2019
1Neoplasm Metastasis (Metastasis)
01/2019
1Glioblastoma (Glioblastoma Multiforme)
01/2019
1Carcinoma (Carcinomatosis)
01/2019
1Parkinson Disease (Parkinson's Disease)
01/2016
1Experimental Arthritis
11/2010
1Pain (Aches)
08/2008
1Neuralgia (Stump Neuralgia)
08/2008
1Peripheral Nerve Injuries
08/2008
1Hyperalgesia
08/2008
1Hypersensitivity (Allergy)
08/2008
1Melanoma (Melanoma, Malignant)
02/2008
1Mania (Manias)
07/2005
1Mood Disorders (Mood Disorder)
07/2005

Drug/Important Bio-Agent (IBA)

5Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
01/2022 - 08/2003
5Insulin (Novolin)FDA Link
01/2021 - 02/2014
5Amyloid beta-PeptidesIBA
01/2017 - 04/2003
4Proteins (Proteins, Gene)FDA Link
10/2021 - 12/2007
4FilaminsIBA
01/2017 - 02/2008
3CalciumIBA
01/2022 - 01/2020
3Apolipoprotein E4IBA
01/2022 - 01/2017
3Brain-Derived Neurotrophic Factor (BDNF)IBA
10/2021 - 01/2016
3CytokinesIBA
01/2021 - 02/2014
3Apolipoproteins E (ApoE)IBA
01/2021 - 04/2012
3Amyloid (Amyloid Fibrils)IBA
01/2017 - 12/2007
2Phospholipases A2 (Phospholipase A2)IBA
01/2022 - 01/2021
2ApolipoproteinsIBA
01/2022 - 01/2017
2tau Proteins (tau Protein)IBA
01/2017 - 08/2003
2SimufilamIBA
01/2017 - 07/2012
2GTP-Binding Proteins (G-Protein)IBA
03/2016 - 07/2005
2S 24795IBA
03/2010 - 01/2009
2N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
01/2009 - 07/2006
2Peptides (Polypeptides)IBA
08/2003 - 04/2003
1tyrosine receptor (receptor, tyrosine)IBA
01/2021
1Pharmaceutical PreparationsIBA
01/2021
1Phosphotransferases (Kinase)IBA
01/2021
1Nitric Oxide Synthase (NO Synthase)IBA
01/2020
1Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2020
1Messenger RNA (mRNA)IBA
01/2020
1Neurotransmitter Agents (Neurotransmitter)IBA
01/2020
1Glutamic Acid (Glutamate)FDA Link
01/2020
1AdiponectinIBA
12/2019
1LeptinIBA
12/2019
1AdipokinesIBA
12/2019
1Insulin ReceptorIBA
01/2019
1Mechanistic Target of Rapamycin Complex 1IBA
01/2019
1LDL Lipoproteins (beta Lipoproteins)IBA
01/2017
1oxidized low density lipoproteinIBA
01/2017
1Toll-Like Receptor 4IBA
01/2017
1Dopamine (Intropin)FDA LinkGeneric
03/2016
1Serotonin (5 Hydroxytryptamine)IBA
03/2016
1Antipsychotic Agents (Antipsychotics)IBA
03/2016
1Guanosine Triphosphate (GTP)IBA
03/2016
1Serine (L-Serine)FDA Link
02/2014
1Glucagon-Like Peptide 1 (GLP 1)IBA
02/2014
1LiraglutideFDA Link
02/2014
1Anesthetics (Anesthetic Agents)IBA
01/2013
1Insulin-Like Growth Factor I (IGF-1)IBA
04/2012
1Biomarkers (Surrogate Marker)IBA
04/2012
1Analgesics (Analgesic Drugs)IBA
11/2010
1Morphine (MS Contin)FDA LinkGeneric
11/2010
1VimentinIBA
11/2009
1Acetylcholine (Acetylcholine Chloride)FDA Link
01/2009
1mu Opioid Receptors (mu Opioid Receptor)IBA
08/2008
1OxytrexIBA
08/2008
1Oxycodone (Oxycontin)FDA LinkGeneric
08/2008
1Opioid Analgesics (Opioids)IBA
08/2008
1Naltrexone (ReVia)FDA LinkGeneric
08/2008
1Fluorescein-5-isothiocyanate (FITC)IBA
02/2008
1Naloxone (Narcan)FDA LinkGeneric
02/2008
1Presenilin-1IBA
12/2007
1Neuregulin-1 (Neuregulin 1)IBA
07/2006
1NeuregulinsIBA
07/2006
1N-Methylaspartate (NMDA)IBA
07/2006
1ErbB Receptors (EGF Receptor)IBA
07/2006
1Protein Kinase CIBA
07/2005
1Valproic Acid (Depakote)FDA LinkGeneric
07/2005
1LithiumIBA
07/2005

Therapy/Procedure

2Oral Administration
11/2010 - 08/2008
1General Anesthesia
01/2013
1Therapeutics
08/2008